Fucose Analog Blocks Hepatoma Invasion (IMAGE)

RIKEN

Fucose Analog Blocks Hepatoma Invasion

Caption

This schematic shows how the glucose analog is able to prevent hepatoma invasion. Normally, fucose (faded red triangle) it is added to glycoproteins through fucosylation, allowing the cancer cells to invade. The analog (red triangle with blue lines) interfered with this process by competing for attention from the FX enzyme, and ultimately preventing fucosylation and subsequent hepatoma invasion.

Credit

RIKEN

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Credit RIKEN

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