Smc5-6 (IMAGE) University of Ottawa Caption By modelling the mutations causing the LIC syndrome in the system, this showed that the mutations affect ability of the Smc5/6 complex to repair chromosomes in cells, thus explaining how LIC mutations affect the ability of cells to maintain healthy genomes. Credit D'Amours Lab/University of Ottawa Usage Restrictions None License Licensed content Disclaimer: AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert system.