fMRI Brain Scan (IMAGE) University of Maryland Caption The brain's posterior cingulate cortex (PCC)/precuneus region is a hub of neuronal networks which integrates and disperses signals. A loss of connectivity to this hub is associated with memory loss and amyloid accumulation, both signs of MCI and Alzheimer's. Credit J. Carson Smith Usage Restrictions None License Licensed content Disclaimer: AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert system.