Tau Control Prevents Alzheimer's Disease in Animal Models (IMAGE)
Caption
Brain section from mouse carrying the dementia-causing P301S mutation in human tau shows accumulation of tau neurofibrillary tangles (in dark brown, left). When Nuak1 levels are decreased by 50 percent (P301S/Nuak1+/-; right), fewer tau tangles accumulate.
Credit
The Zoghbi lab/Baylor College of Medicine
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