Karyotype (IMAGE)
Caption
Photograph of a karyotype - the collection of chromosomes within each cell of an organism - from a male mouse engineered by Johns Hopkins Medicine researchers to model Down syndrome in a human. The rodent possesses the 20 pairs of chromosomes (including the XY pair at the end that determines gender) normally seen in a mouse plus a piece of chromosome 21 from a human cell (indicated by the yellow arrow). Down syndrome occurs in humans when there is an extra partial or entire copy of the 21st chromosome.
Credit
Johns Hopkins Medicine
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