Long-Term Contraception in a Single Shot (IMAGE) California Institute of Technology Caption Caltech biologists have developed a nonsurgical method to deliver long-term contraception to both male and female animals with a single shot. The technique -- so far used only in mice -- holds promise as an alternative to spaying and neutering feral animals. Here, an antibody bound to the egg zona pellucida (indicated in blue), a binding site for sperm, results in infertility. Credit Bruce Hay/Caltech Usage Restrictions None License Licensed content Disclaimer: AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert system.