Schematic Drawing of the Transmembrane Portion of TMEM16 Family Proteins (IMAGE)
Caption
Schematic drawing of the transmembrane portion of TMEM16 family proteins. Upper panel shows a scramblase, in closed (nonconductive) intermediate (ion conduction) and open (lipid exchange) configuration. The lower panel shows an ion channel, which can only take on the closed and intermediate configuration.
Credit
C. Paulino, University of Groningen
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