Two-Photon in vivo Imaging of Meissner's Corpuscle Mechanoreceptor in the Fingertip of a Mouse Paw (IMAGE)

Nagoya Institute of Technology

Two-Photon in vivo Imaging of Meissner's Corpuscle Mechanoreceptor in the Fingertip of a Mouse Paw

Caption

MCs were labeled with a fluorescent lipophilic dye (orange) and imaged in living tissue by two-photon excitation microscopy (green). MCs are located in finger-like projections of the dermis called dermal papillae. Each MC consists of connective tissue-encapsulated nerve endings, which branch from a single nerve fiber, which itself branches from an afferent axon. (Figure is not drawn to scale)

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NITech

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