Behavioral Expression of Fear Memory (1 of 2) (IMAGE)
Caption
Behavi oral expression of fear memory: In n aïve (unlearned) state, mice have not gained a context - specific engram. In the learned memory state, mice have acquired a synapticaly potentiated fear engram, which causes them to express freezing be havior in the fearful context. In the amnesia state, protein synthesis inhibition has resulted in mice that have an interrupted and synaptically depotentiated fear engram, which does not cause freezing behavior in the fearful context, but can resul t in freezing behavior if directly activated.
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[Credit: Dheeraj Roy ]
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