Higher Inflammation & Protein Turnover in Skin Disorder DEB (IMAGE)

American Society for Biochemistry and Molecular Biology

Higher Inflammation & Protein Turnover in Skin Disorder DEB

Caption

Researchers comparing protein expression in skin tissue from patients with dystrophic epodermolysis bullosa (DEB), which causes blistering and scarring, to tissue from healthy controls have shown increased inflammation and proteolysis in patient tissue. The proteomic results may uncover future treatment strategies for the rare genetic disorder, caused by mutation to collagen VII.

Credit

Kerstin Thriene and Jörn Dengjel, Department of Dermatology, Medical Center, University of Freiburg, Germany

Usage Restrictions

None

License

Licensed content

Disclaimer: AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert system.