Targeted Protein Degradation Approach (IMAGE)

Walter and Eliza Hall Institute

Targeted Protein Degradation Approach

Caption

In the Targeted Protein Degradation approach, a small drug molecule (pink, centre) is developed that can destroy a disease-causing protein (orange, left) by bringing it into proximity with part of the cell's protein recycling machinery (multicolored, right), such as an IAP protein.

Credit

Dr. Michael Roy (WEHI), using UCSF ChimeraX.

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