Scorpion-Derived Peptides Deliver Arthritis Drugs to Joints Without Systemic Toxicity (3 of 3) (IMAGE)

American Association for the Advancement of Science (AAAS)

Scorpion-Derived Peptides Deliver Arthritis Drugs to Joints Without Systemic Toxicity (3 of 3)

Caption

Infographic showing how a future treatment of arthritis could involve using a scorpion-derived mini-protein (a peptide) that delivers arthritis drugs directly to joint cartilage. The approach could potentially improve the safety of arthritis treatment. This material relates to a paper that appeared in the Mar. 4, 2020, issue of Science Translational Medicine, published by AAAS. The paper, by M.L. Cook-Sangar at Fred Hutchinson Cancer Research Center in Seattle, WA; and colleagues was titled, "A potent peptide-steroid conjugate accumulates in cartilage and reverses arthritis without evidence of systemic corticosteroid exposure."

Credit

Fred Hutchinson Cancer Research Center

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