Architectural Changes in Reprogramming (IMAGE) Center for Genomic Regulation Caption Architectural changes in chromosome 13 around the pluripotency stem cell gene Sox2 (yellow ball) during reprogramming of blood cells (left) into induced pluripotent cells (right). Credit Marco Di Stefano, CNAG-CRG. Usage Restrictions CC-BY License Licensed content Disclaimer: AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert system.