Base editing for progeria treatment (IMAGE)

NIH/National Human Genome Research Institute

Base editing for progeria treatment

Caption

Progeria is caused by a mutation in the nuclear lamin A gene in which one DNA base C is changed to a T. Researchers used the base editing method, which substitutes a single DNA letter for another without damaging the DNA, to reverse that change.

Credit

Ernesto del Aguila III, NHGRI

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