Simulation Video (VIDEO) Simons Foundation This video is under embargo. Please login to access this video. Caption A simulation of a tangled ball of chromatin encased in a spherical nucleus. As molecular machines extend segments of the chromatin, large regions shift in unison. Credit D. Saintillan, M.J. Shelley and A. Zidovska/PNAS 2018 Usage Restrictions None License Licensed content Disclaimer: AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert system.