Reaching a New Checkpoint in Immunotherapy Treatment (1 of 1) (IMAGE)

American Association for the Advancement of Science (AAAS)

Reaching a New Checkpoint in Immunotherapy Treatment (1 of 1)

Caption

Overview of the sensitization approach: Transforming non-responsive tumors to increase NK cell recruitment and STAT1 activation makes them more sensitive to checkpoint blockade. This material relates to a paper that appeared in the Jul. 17, 2019, issue of Science Translational Medicine, published by AAAS. The paper, by R.M. Zemek at University of Western Australia in Crawley, WA, Australia; and colleagues was titled, 'Sensitization to immune checkpoint blockade through activation of a STAT1/NK axis in the tumor microenvironment.'

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