Neuronal cell line (IMAGE) Ecole Polytechnique Fédérale de Lausanne Caption Neuronal cell line (mHypoE-N41) transfected with NPY-mCherry (in red) and stained with phalloidin to label the actin cytoskeleton (in green). In this cell TGR5 was activated by its selective agonist INT-777 and this activation caused the stabilization and polymerization of the actin fibers (green) and the consequent accumulation of NPY (in red) in the cytoplasm and block of its release. Credit EPFL Usage Restrictions None License Licensed content Disclaimer: AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert system.