Designer Barrel Proteins (IMAGE) University of Bristol Caption The orthogonal views of 5-, 6- and 7-helix barrel proteins created by Drew Thomson, Dek Woolfson and colleagues at the University of Bristol, UK, and described this week in Science. The images show the central channels in these structures to which the team aim to add functions in future. Credit Woolfson group, University of Bristol, UK Usage Restrictions The image is for single use only to illustrate articles on the <i>Science</i> article ‘Computational design of water-soluble α–helical barrels’ by Thomson A.R. et al and is not to be archived. Please credit the copyright holder: Woolfson group, University of Bristol, UK. License Licensed content Disclaimer: AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert system.