Nerve Cells Deficient in STIM1 (STIM1-KO) (IMAGE) University of Extremadura Caption The scientists have found a deficiency in the protein STIM1 in brain tissue from patients with Alzheimer's disease. Its involvement in neurodegenerative processes has been verified thanks to the technique CRISPR/Cas9. Up to now, the effects of a deficiency in this protein critical to sporadic Alzheimer's were not known. Credit UEx Usage Restrictions None License Licensed content Disclaimer: AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert system.