Early Phosphate Metabolism (IMAGE) Cell Press Caption This is a schematic depiction of how an early metabolism could have expanded from an initial set of prebiotic molecules, with thioester (S) vs. phosphate (P) as the main driving force. Credit Joshua Goldford and Daniel Segrè Usage Restrictions Credit Required. License Licensed content Disclaimer: AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert system.