Cell-Cell Junctions (IMAGE) Cold Spring Harbor Laboratory Press Caption Tight junctions and EGF receptor localization in mouse epidermis: whole-mount immunohistochemistry image of newborn epidermis stained for the tight junctional protein ZO-1 (red) and the EGFR tyrosine kinase receptor (EGFR, green). EGFR colocalizes at or near the tight junctional barrier in the granular layer of the epidermis. Confocal image of selected stacks of a 3D image. Credit Image provided by Matthias Rübsam and Carien M. Niessen, University of Cologne. Usage Restrictions None License Licensed content Disclaimer: AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert system.