SV Distribution within the P16 -P19 Calyx (IMAGE)

Max Planck Florida Institute for Neuroscience

SV Distribution within the P16 -P19 Calyx

Caption

A, B, Schematic diagram showing SVs at different priming states located at different distance to the Ca 2+ source. Only the SVs that locate close to the Ca 2+ source can be released by AP. We propose that either a single AZ contains a mixture of fast and slow SVs (A) or that there are individual AZs within the calyx that contain only fast or only slow pool SVs (B). In both cases, we propose that distal SVs are rapidly converted to fast pool SVs for AP-evoked release to maintain signaling at high firing rates.

Credit

Max Planck Florida Institute for Neuroscience; Dr. Samuel M. Young, Jr.

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