Alcohol and REG3 (IMAGE)

Cell Press

Alcohol and REG3

Caption

The mechanism by which chronic alcohol consumption alters the microbial composition in the intestine is unknown. This visual abstract depicts how alcohol reduces intestinal expression of REG3 lectins, increasing the number of mucosa-associated bacteria. The subsequent translocation of bacteria to mesenteric lymph nodes and liver exacerbates alcoholic liver disease.

Credit

Wang et al./<i>Cell Host & Microbe</i> 2016

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