Gene Expression Signature (IMAGE) Universidad Carlos III de Madrid Caption Gene expression signature in fibroblasts from RDEB, KS and XPC patients, compared to healthy donors (a). An alteration common to the three diseases of 227 genes was identified (b; c), particularly showing those associated with changes in the extracellular matrix (d). Credit UC3M Usage Restrictions None License Licensed content Disclaimer: AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert system.