Switching on One-Shot Learning (IMAGE) California Institute of Technology Caption Caltech researchers provide evidence that the amount of uncertainty about the causal relationship between a stimulus and an outcome mediates switching between incremental learning, in which we gradually acquire knowledge, and one-shot learning, where we rapidly learn from a single pairing of a potential stimulus and an outcome. Neuroimaging findings suggest that the ventrolateral prefrontal cortex may act as a "switch," selectively turning one-shot learning on and off, as needed. Credit Sang Wan Lee/Caltech Usage Restrictions None License Licensed content Disclaimer: AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert system.