Clathrin-Mediated Endocytosis (IMAGE) National University of Singapore Caption An artist's impression of Clathrin-Mediated Endocytosis (CME) occurring as periodic traveling waves on the membrane. Clathin coated vesicles (blue) bud off from wave peaks. Clathrin waves require intermediate PIP3 levels (red) and also feedback from downstream components of cortical wave machinery such as FBP17 (green). Credit Mechanobiology Institute, Singapore Usage Restrictions Credit image accordingly to: Mechanobiology Institute, Singapore License Licensed content Disclaimer: AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert system.