How Bacteria Kill Host Cells from the Inside (IMAGE)

PLOS

How Bacteria Kill Host Cells from the Inside

Caption

Model for intramacrophage fate of P. aeruginosa. Phagocytosed P. aeruginosa PAO1 first resides in a vacuole, before escaping the phagosome and promoting macrophage lysis. Live imaging of macrophages infected with fluorescent P. aeruginosa allows to follow the lysis of a specific macrophage (white arrow on the picture). MgtC and OprF act positively on the expression of T3SS, which is involved in cell lysis driven by intracellular P. aeruginosa through the ExoS protein.

Credit

Anne Blanc-Potard

Usage Restrictions

CC-BY: Redistribution permitted with credit

License

Licensed content

Disclaimer: AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert system.