When Healing Goes Haywire: Protein Found that Slows Fibrosis (2 of 4) (IMAGE)

American Association for the Advancement of Science (AAAS)

When Healing Goes Haywire: Protein Found that Slows Fibrosis (2 of 4)

Caption

Conditional macrophage ablation inhibits kidney fibrosis in ureteral obstruction. Photomicrographs of F4/80 immunostaining for macrophages or Sirius red staining for fibrosis in CD11b-DTR kidneys treated with DT or vehicle to ablate macrophages on d10 after UUO. This image relates to an article that appeared in the Nov. 4, 2009, issue of Science Translational Medicine. The study, by Dr. Ana P. Castano of Harvard Institutes of Medicine, Harvard Medical School, and Brigham and Women's Hospital in Boston, and colleagues was titled, "Serum Amyloid P Inhibits Fibrosis Through FcgR-Dependent Monocyte-Macrophage Regulation in Vivo."

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[Image courtesy of <i>Science</i>/AAAS]

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