Perforin and Metabolism (IMAGE)

Cell Press

Perforin and Metabolism

Caption

Perforin-positive dendritic cells (perf- DCs) represent a minor subpopulation of myeloid DCs. Based on selective ablation of perf-DCs in radiation chimera, Reisner and colleagues demonstrate that these cells control inflammatory T cells in steady state and play a regulatory role in metabolic syndrome and in experimental autoimmune encephalomyelitis.

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Reisner et al./<i>Immunity</i> 2015

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