Degradation of Ucp1 mRNA in Fat Cells (VIDEO)

Okinawa Institute of Science and Technology (OIST) Graduate University

Caption

The animation illustrates OIST's findings in obesity: the degradation of Ucp1 mRNA in fat cells is mediated by Tob and Cnot7, which are recruited by BRF1. The decrease in Ucp1 is one of the contributing factors to obesity in mice and humans.

Credit

Letizia Diamante, Juna Kurihara, flaticon

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