Effects of ar-turmerne derivatives on IFNγ/LPS-induced dopaminergic neurodegeneration in rat midbrain slice cultures (IMAGE)

Kumamoto University

Effects of ar-turmerne derivatives on IFNγ/LPS-induced dopaminergic neurodegeneration in rat midbrain slice cultures

Caption

<p>A: Immunostained images of tyrosine hydroxylase (TH), a dopaminergic marker, in midbrain slice cultures co-treated with IFN&gamma;/LPS and ar-turmerone derivatives. (Scale bar: 100 micrometers) </p> <p>B: Quantitative analysis of dopaminergic neuron count. </p> <p>C: Quantitative analysis of NO production from midbrain slice cultures. (* p < 0.05, *** p < 0.001 vs. control, ### p < 0.001 (n = 6-9, one-way ANOVA, followed by a post hoc Tukey test)) </p>

Credit

Associate Professor Takahiro Seki

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<p>Adapted from Fig. 3 (A, B & C) of <a href="https://www.mdpi.com/2073-4409/10/5/1090">Hori, Y. et.al., Cells, 2021</a>. </p> <p>This image is made available under the terms of <a href="https://creativecommons.org/licenses/by/4.0/">CC by 4.0</a>. Any further distribution of this work must follow the terms of this license. </p>

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