PR ABJ CA State (IMAGE) DOE/Lawrence Berkeley National Laboratory Caption Structure of the human Polycomb Repressive Complex 2 (PRC2) bound to cofactors obtained by cryo-electron microscopy. Both cofactors mimic the histone protein tail to stabilize and stimulate the enzymatic activity of PRC2. Credit (Credit: Vignesh Kasinath) Usage Restrictions Editorial Use Only License Licensed content Disclaimer: AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert system.