Commensal Bacteria and Colonic Tissue (IMAGE) PLOS Caption Left, commensal bacteria (red) in the intestine are kept at a distance from the colonic tissue by a thick layer of mucus (green). Antibiotics perturb the integrity of the mucus layer, facilitating invasion by some bacterial species such as Klebsiella pneumoniae (middle) and to a lesser extend VRE (right). Infiltration of the colonic mucus layer may prove to be a critical step in bacterial spread to other sites including the bloodstream. Credit Silvia Caballero, CC-BY Usage Restrictions None License Licensed content Disclaimer: AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert system.