Mice Spleens (IMAGE) University of California - San Diego Caption In mice with Muckle-Well syndrome, an inflammatory condition caused by mutations in NLRP3 genes, treatment with a choline kinase inhibitor reduces inflammation, as evidenced by the smaller spleens on the right, compared to mock-treated mice (three larger spleens on left). Credit UC San Diego Usage Restrictions None License Licensed content Disclaimer: AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert system.