Mutation Pinpoints Autoimmunity as a Culprit in ALS (IMAGE)

American Association for the Advancement of Science (AAAS)

Mutation Pinpoints Autoimmunity as a Culprit in ALS

Caption

A new study reports that the most common genetic mutation found in amyotrophic lateral sclerosis (ALS) patients causes deadly autoimmune disease in mice, pinpointing autoimmunity as a potential culprit in ALS. This material relates to a paper that appeared in the July 13 issue of Science Translational Medicine, published by AAAS. The paper, by A. Burberry at Harvard University in Cambridge, MA, and colleagues was titled, "Loss-of-function mutations in the C9ORF72 mouse ortholog cause fatal autoimmune disease."

Credit

V. Altounian / <i>Science Translational Medicine</i> (2016)

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