Ring Cycle (VIDEO) Rockefeller University This video is under embargo. Please login to access this video. To view this video please enable JavaScript, and consider upgrading to a web browser that supports HTML5 video Caption The octagonal center ring of the nuclear pore complex opens when nucleoporin 58 (red) interacts with nucleoporin 54 (blue), then constricts as they separate. New research shows unstructured regions of 58 (squiggly filaments) interact with transport factors (green). This interaction makes the dilated conformation more favorable, pushing the ring to open. Credit The Laboratory of Cell Biology Usage Restrictions Video may only be used to illustrate research described in the accompanying release. License Licensed content Disclaimer: AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert system.