figure1 (IMAGE) Kanazawa University Caption Schematic drawing of polyclonal metastasis. Metastatic cells generate metastatic niche by activation of hepatic stellate cells (HSCs). Non-metastatic cells can survive and proliferate with the presence of such metastatic niche, resulting in polyclonal metastasis development. Credit Kanazawa University Usage Restrictions The image may only be used with appropriate caption and credit. License Licensed content Disclaimer: AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert system.