Scheme 1 (IMAGE)

Pohang University of Science & Technology (POSTECH)

Scheme 1

Caption

Schematic illustration of the reinforced natural killer cell (ReNK) system and its anti?cancer effect upon encountering cancer cells. NK cells reinforced with doxorubicin (DOX)?loaded, acid?responsive micelles, home onto the tumor site. When an NK cell engages a cancer cell, an immunological synapse is formed, and acidic granules are released by the former into the synapse. Acidification of the synapse induces the release of DOX from the micelles and its diffusion into the tumor site.

Credit

Won Jong Kim (POSTECH)

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