The Atomic Structure of C5 Bound to the C5-Binding Part of Eculizumab (IMAGE)

Aarhus University

The Atomic Structure of C5 Bound to the C5-Binding Part of Eculizumab

Caption

The atomic structure of C5 (blue) bound to the C5-binding part of eculizumab (yellow) shows how eculizumab blocks the cleavage of C5 in blood circulation. This rescues the red blood cells (red disks) from disruption. In real life the proteins are 500 times smaller than the red blood cells.

Credit

Janus Asbjørn Schatz-Jakobsen

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