Cells tunneling (VIDEO)

Cell Press

Caption

This video shows immune cells tunneling through surrounding tissue. CTLs (bead-stimulated primary human CD8+ T cells) were transiently transfected with mCherry (red). Collagen (5 mg/ml) was stained with Atto 488 NHS (left: in green, right: in grey). CTL migration was visualized using lightsheet microscopy with a 20X objective at 37oC with an interval of 30 sec. A z-stack was acquired with a step size of 1 microns. One layer is shown here. Time stamp is HH:MM:SS. Scale bar is 10 microns.

Credit

Sadjadi et al Biophysical Journal

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