PD Astrocytes (IMAGE)

University of Eastern Finland

PD Astrocytes

Caption

PD patients' astrocytes manifest several hallmarks of the disease, these include: (1) increased production of alpha-synuclein, (2) increased reactivity upon inflammatory stimulation, (3) increased astrocytic Ca2+ levels, (4) mtDNA maintenance defects and (5) metabolomic changes.

Credit

Tuuli-Maria Sonninen

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