Towards More Effective Therapies to Fight Breast Cancer (IMAGE)

Scuola Internazionale Superiore di Studi Avanzati

Towards More Effective Therapies to Fight Breast Cancer

Caption

The image represents the human aromatase (on the right side), an enzyme involved in hormone biosynthesis, with its in/out ligand channels (in yellow and magenta) travelled by letrozole, a last generation inhibitor clinically used against breast cancer (left side) and androstenedione (on the bottom right side), one of the molecules that aromatase converts to estrogens.

Credit

Alessandra Magistrato and Lorenzo Casalino, CNR-IOM and SISSA, Trieste, Italy

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