A Man's Weight Affects Sperm Epigenetics (IMAGE)

Cell Press

A Man's Weight Affects Sperm Epigenetics

Caption

This visual abstract shows how spermatozoa from obese men carry a distinct epigenetic signature compared to lean men, in particular at genes controlling brain development and function. The sperm methylome is dynamically remodeled after gastric-bypass-induced weight loss, notably at gene regions implicated in the central control of appetite.

Credit

Donkin and Versteyhe et al./<i>Cell Metabolism</i> 2015

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