Swarming Neutrophils in tissue (VIDEO)
Caption
Individual neutrophils (cyan) attract more cells to initiate the formation of a neutrophil swarm and cluster (pink) in living mouse tissue (blue). Researchers from the MPI of Immunobiology and Epigenetics in Freiburg decipher the basic biology of neutrophil swarming and now show that the cells also evolved an intrinsic molecular program to self-limit their swarming activity. The study published in the scientific journal Science elucidates how swarming neutrophils become insensitive to their own secreted signals that brought the swarm together in the first place. This process is crucial for the efficient elimination of bacteria in tissues.
Credit
MPI of Immunobiology & Epigenetics, T. Lämmermann
Usage Restrictions
Please use with appropriate caption and credit.
License
Licensed content