VP35 Mutant Ebola Virus Vaccine (IMAGE)
Caption
This visual abstract depicts the work that demonstrates that immune evasion functions of the VP35 protein of the Ebola virus are critical for virulence in non-human primates. A VP35 mutant Ebola virus does not cause lethal disease and instead elicits adaptive immune responses that can protect animals from wild-type Ebola virus challenge.
Credit
Woolsey and Menicucci et al./Cell Reports
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