Glutaminyl tRNA Synthetase (IMAGE)
Caption
Crystal structure of glutaminyl tRNA synthetase (GlnRS, green) in complex with its substrate tRNA^Gln (yellow). Left panel: Color-coded residues depict favorable (blue) and unfavorable (red) effects on the free energy of glutamine binding from mutation at this position. Right panel: Effects of mutation on the ability of GlnRS to catalyze amino acid attachment to the tRNA. In this case all effects are unfavorable.
Credit
Annia Rodriguez/ John Perona / UCSB
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