The optimized boronic acid inhibitor (IMAGE) The Francis Crick Institute Caption The optimized boronic acid inhibitor shown covalently bound into the active site of SUB1. Hydrogen bonds between the inhibitor and the enzyme are shown as dotted lines. Credit Chrislaine Withers-Martinez Usage Restrictions With credit License Licensed content Disclaimer: AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert system.