The Future of Multiplexed Gene Editing (IMAGE)

Wyss Institute for Biologically Inspired Engineering at Harvard

The Future of Multiplexed Gene Editing

Caption

Harvard's Wyss Institute collaborates with Cytosurge to enable multiplexed genome editing. Up until now, the delivery of genome editing agents like CRISPR-Cas9 (lavender) using delivery vectors (pink), and allowing it to edit several target sequences in the genome (blue) simultaneously often causes cells to fail in their functions and die. The collaboration investigates whether nanoinjection methods of the reagents into distinct locations of the cell, including its cytoplasm and nucleus, and in defined amounts, would allow higher-order multiplexed edits to the genome.

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Wyss Institute at Harvard University

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