FACT Protein Complex (IMAGE)

Lomonosov Moscow State University

FACT Protein Complex

Caption

This is an image of the functioning of FACT protein complex. FACT protein complex is a chaperon of histones, i.e. a factor that as a rule stabilizes nucleosome. However, the presence of a small DNA-binding protein Nhp6 radically changes the function of FACT by untwisting the nucleosome. This change in activity was demonstrated both for yeast and human FACT.

Credit

Maria Valieva

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