Comparison of AsqJ Variants (IMAGE)

Technical University of Munich (TUM)

Comparison of AsqJ Variants

Caption

While the difference between the natural and the modified AsqJ is only one amino acid, the reactivity is clearly different. The natural AsqJ (left) possesses a valine at position 72 (blue). The modified form possesses an isoleucine (red) at position 72. The substrate in the active site is green-colored, alpha-ketoglutarate yellow, the iron atom gray, and two histidine chains cyan and blue.

Credit

Sophie Mader/TUM

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